Zembutsu, Hitoshi: search on Z-Library

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1

Expression profiles of non-small cell lung cancers on cDNA microarrays: Identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs

Kikuchi, Takefumi, Daigo, Yataro, Katagiri, Toyomasa, Tsunoda, Tatsuhiko, Okada, Koichi, Kakiuchi, Soji, Zembutsu, Hitoshi, Furukawa, Yoichi, Kawamura, Masafumi, Kobayashi, Koichi

Journal:

Year:

2003

Language:

english

File:

PDF, 730 KB

english, 2003

2

Genome-wide association study of epirubicin-induced leukopenia in Japanese patients

Srinivasan, Yuvaraj, Sasa, Mitsunori, Honda, Junko, Takahashi, Atsushi, Uno, Satoko, Kamatani, Naoyuki, Kubo, Michiaki, Nakamura, Yusuke, Zembutsu, Hitoshi

Journal:

Pharmacogenetics and Genomics

Year:

2011

Language:

english

File:

PDF, 230 KB

english, 2011

3

Research Highlights

Zembutsu, Hitoshi

Journal:

Pharmacogenomics

Year:

2011

Language:

english

File:

PDF, 485 KB

english, 2011

4

The prediction models for postoperative overall survival and disease-free survival in patients with breast cancer

Shigemizu, Daichi, Iwase, Takuji, Yoshimoto, Masataka, Suzuki, Yasuyo, Miya, Fuyuki, Boroevich, Keith A, Katagiri, Toyomasa, Zembutsu, Hitoshi, Tsunoda, Tatsuhiko

Journal:

Cancer Medicine

Year:

2017

Language:

english

File:

PDF, 667 KB

english, 2017

5

Determination of novel CYP2D6 haplotype using the targeted sequencing followed by the long-read sequencing and the functional characterization in the Japanese population

Fukunaga, Koya, Hishinuma, Eiji, Hiratsuka, Masahiro, Kato, Ken, Okusaka, Takuji, Saito, Takeo, Ikeda, Masashi, Yoshida, Teruhiko, Zembutsu, Hitoshi, Iwata, Nakao, Mushiroda, Taisei

Journal:

Journal of Human Genetics

Year:

2020

File:

PDF, 718 KB

2020

6

Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients

Low, Siew-Kee, Kiyotani, Kazuma, Mushiroda, Taisei, Daigo, Yataro, Nakamura, Yusuke, Zembutsu, Hitoshi

Journal:

Journal of Human Genetics

Year:

2009

Language:

english

File:

PDF, 138 KB

english, 2009

7

A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population

Nakashima, Mitsuko, Chung, Suyoun, Takahashi, Atsushi, Kamatani, Naoyuki, Kawaguchi, Takahisa, Tsunoda, Tatsuhiko, Hosono, Naoya, Kubo, Michiaki, Nakamura, Yusuke, Zembutsu, Hitoshi

Journal:

Nature Genetics

Year:

2010

Language:

english

File:

PDF, 780 KB

english, 2010

8

A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese

Uno, Satoko, Zembutsu, Hitoshi, Hirasawa, Akira, Takahashi, Atsushi, Kubo, Michiaki, Akahane, Tomoko, Aoki, Daisuke, Kamatani, Naoyuki, Hirata, Koichi, Nakamura, Yusuke

Journal:

Nature Genetics

Year:

2010

Language:

english

File:

PDF, 344 KB

english, 2010

9

The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors

Nishimori, Hiroyuki, Sasaki, Yasushi, Yoshida, Koichi, Irifune, Hideto, Zembutsu, Hitoshi, Tanaka, Toshihiro, Aoyama, Tomoki, Hosaka, Taisuke, Kawaguchi, Satoshi, Wada, Takuro

Journal:

Year:

2002

Language:

english

File:

PDF, 301 KB

english, 2002

10

Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression

Cha, Pei-Chieng, Mushiroda, Taisei, Zembutsu, Hitoshi, Harada, Hiromasa, Shinoda, Noriyuki, Kawamoto, Shunji, Shimoyama, Rai, Nishidate, Toshihiko, Furuhata, Tomohisa, Sasaki, Kazuaki

Journal:

Journal of Human Genetics

Year:

2009

Language:

english

File:

PDF, 234 KB

english, 2009

11

Whole genome sequencing to identify predictive markers for the risk of drug-induced interstitial lung disease

Udagawa, Chihiro, Horinouchi, Hidehito, Shiraishi, Kouya, Kohno, Takashi, Okusaka, Takuji, Ueno, Hideki, Tamura, Kenji, Ohe, Yuichiro, Zembutsu, Hitoshi, Labib, Rania Mohamed

Journal:

Year:

2019

Language:

english

File:

PDF, 926 KB

english, 2019

12

Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy

Kazuma Kiyotani, Taisei Mushiroda, Mitsunori Sasa, Yoshimi Bando, Ikuko Sumitomo, Naoya Hosono, Michiaki Kubo, Yusuke Nakamura, Hitoshi Zembutsu

Journal:

Year:

2008

Language:

english

File:

PDF, 136 KB

english, 2008

13

Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan

Low, Siew-Kee, Chung, Suyoun, Takahashi, Atsushi, Zembutsu, Hitoshi, Mushiroda, Taisei, Kubo, Michiaki, Nakamura, Yusuke

Journal:

Year:

2013

Language:

english

File:

PDF, 225 KB

english, 2013

14

Impact of LIMK1, MMP2 and TNF-α variations for intracranial aneurysm in Japanese population

Low, Siew-Kee, Zembutsu, Hitoshi, Takahashi, Atsushi, Kamatani, Naoyuki, Cha, Pei-Chieng, Hosono, Naoya, Kubo, Michiaki, Matsuda, Koichi, Nakamura, Yusuke

Journal:

Journal of Human Genetics

Year:

2011

Language:

english

File:

PDF, 291 KB

english, 2011

15

Lymph node shape in computed tomography imaging as a predictor for axillary lymph node metastasis in patients with breast cancer

KUTOMI, GORO, OHMURA, TOUSEI, SATOMI, FUKINO, TAKAMARU, TOMOKO, SHIMA, HIROAKI, SUZUKI, YASUYO, OTOKOZAWA, SEIKO, ZEMBUTSU, HITOSHI, MORI, MITSURU, HIRATA, KOICHI

Journal:

Experimental and Therapeutic Medicine

Year:

2014

Language:

english

File:

PDF, 376 KB

english, 2014

16

Should CYP2D6 inhibitors be administered in conjunction with tamoxifen?

Zembutsu, Hitoshi, Sasa, Mitsunori, Kiyotani, Kazuma, Mushiroda, Taisei, Nakamura, Yusuke

Journal:

Expert Review of Anticancer Therapy

Year:

2011

Language:

english

File:

PDF, 499 KB

english, 2011

17

Breast cancer: The translation of big genomic data to cancer precision medicine

Low, Siew-Kee, Zembutsu, Hitoshi, Nakamura, Yusuke

Journal:

Year:

2017

Language:

english

File:

PDF, 399 KB

english, 2017

18

Targeted sequencing reveals genetic variants associated with sensitivity of 79 human cancer xenografts to anticancer drugs

Udagawa, Chihiro, Sasaki, Yasushi, Suemizu, Hiroshi, Ohnishi, Yasuyuki, Ohnishi, Hiroshi, Tokino, Takashi, Zembutsu, Hitoshi

Journal:

Experimental and Therapeutic Medicine

Year:

2017

Language:

english

File:

PDF, 469 KB

english, 2017

19

Possible involvement of NEDD4 in keloid formation; its critical role in fibroblast proliferation and collagen production

CHUNG, Suyoun, NAKASHIMA, Mitsuko, ZEMBUTSU, Hitoshi, NAKAMURA, Yusuke

Journal:

Proceedings of the Japan Academy Series B Physical and Biological Sciences

Year:

2011

Language:

english

File:

PDF, 618 KB

english, 2011

20

Whole genome sequencing to identify predictive markers for the risk of drug-induced interstitial lung disease

Udagawa, Chihiro, Horinouchi, Hidehito, Shiraishi, Kouya, Kohno, Takashi, Okusaka, Takuji, Ueno, Hideki, Tamura, Kenji, Ohe, Yuichiro, Zembutsu, Hitoshi, Labib, Rania Mohamed

Journal:

Year:

2019

File:

PDF, 926 KB

2019

21

Tubular adenoma of the breast in a 73-year-old Woman

Hidefumi Nishimori, Mayumi Sasaki, Koichi Hirata, Hitoshi Zembutsu, Takahiro Yasoshima, Rika Fukui, Kenji Kobayashi

Journal:

Year:

2000

Language:

english

File:

PDF, 1.02 MB

english, 2000

22

Important and critical scientific aspects in pharmacogenomics analysis: lessons from controversial results of tamoxifen and CYP2D6 studies

Kiyotani, Kazuma, Mushiroda, Taisei, Zembutsu, Hitoshi, Nakamura, Yusuke

Journal:

Journal of Human Genetics

Year:

2013

Language:

english

File:

PDF, 385 KB

english, 2013

23

MP49-13 SELECTIVE NEOADJUVANT CHEMOTHERAPY BY PREDICTION SYSTEMS IMPROVES THE CHEMO-SENSITIVITY OF THE MUSCLE INVASIVE BLADDER CANCERS

Kato, Yoichiro, Zembutsu, Hitoshi, Takata, Ryo, Matsuura, Tomohiko, Kato, Renpei, Kanehira, Mitsugu, Iwasaki, Kazuhiro, Sugimura, Jun, Omori, So, Abe, Takaya, Nakamura, Yusuke, Obara, Wataru

Journal:

The Journal of Urology

Year:

2016

Language:

english

File:

PDF, 172 KB

english, 2016

24

A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese

Elgazzar, Seham, Zembutsu, Hitoshi, Takahashi, Atsushi, Kubo, Michiaki, Aki, Fuminori, Hirata, Koichi, Takatsuka, Yuichi, Okazaki, Minoru, Ohsumi, Shozo, Yamakawa, Takashi, Sasa, Mitsunori, Katagiri,

Journal:

Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 422 KB

english, 2012

25

Pharmacogenomics of Tamoxifen: Roles of Drug Metabolizing Enzymes and Transporters

Kiyotani, Kazuma, Mushiroda, Taisei, Nakamura, Yusuke, Zembutsu, Hitoshi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2012

Language:

english

File:

PDF, 203 KB

english, 2012

26

Clinical relevance of circulating tumor DNA assessed through deep sequencing in patients with metastatic colorectal cancer

Osumi, Hiroki, Shinozaki, Eiji, Takeda, Yoshinori, Wakatsuki, Takeru, Ichimura, Takashi, Saiura, Akio, Yamaguchi, Kensei, Takahashi, Shunji, Noda, Tetsuo, Zembutsu, Hitoshi

Journal:

Cancer Medicine

Year:

2018

Language:

english

File:

PDF, 259 KB

english, 2018

27

1439 A PROSPECTIVE STUDY TO EXAMINE THE AVAILABILITY OF THE PREDICTION SYSTEM OF NEOADJUVANT CHEMOTHERAPY FOR MUSCLE INVASIVE BLADDER CANCER

Kato, Yoichiro, Zembutsu, Hitoshi, Takata, Ryo, Iwasaki, Kazuhiro, Obara, Wataru, Nakamura, Yusuke, Fujioka, Tomoaki

Journal:

The Journal of Urology

Year:

2013

Language:

english

File:

PDF, 159 KB

english, 2013

28

Pharmacogenetics for severe adverse drug reactions induced by molecularâtargeted therapy

Udagawa, Chihiro, Zembutsu, Hitoshi

Journal:

Year:

2020

File:

PDF, 559 KB

2020

29

Serum estradiol should be monitored not only during the peri-menopausal period but also the post-menopausal period at the time of aromatase inhibitor administration

Taeko Nagao, Misako Kira, Masako Takahashi, Junko Honda, Toshiyuki Hirose, Akira Tangoku, Hitoshi Zembutsu, Yusuke Nakamura, Mitsunori Sasa

Journal:

World Journal of Surgical Oncology

Year:

2009

Language:

english

File:

PDF, 585 KB

english, 2009

30

A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients

Chung, Suyoun, Low, Siew-Kee, Zembutsu, Hitoshi, Takahashi, Atsushi, Kubo, Michiaki, Sasa, Mitsunori, Nakamura, Yusuke

Journal:

Breast Cancer Research

Year:

2013

Language:

english

File:

PDF, 222 KB

english, 2013

31

Whole exome sequencing to identify genetic markers for trastuzumab-induced cardiotoxicity

Udagawa, Chihiro, Nakamura, Hiromi, Ohnishi, Hiroshi, Tamura, Kenji, Shimoi, Tatsunori, Yoshida, Masayuki, Yoshida, Teruhiko, Totoki, Yasushi, Shibata, Tatsuhiro, Zembutsu, Hitoshi

Journal:

Year:

2018

Language:

english

File:

PDF, 230 KB

english, 2018

32

Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy

Zembutsu, Hitoshi, Yanada, Masamitsu, Hishida, Asahi, Katagiri, Toyomasa, Tsuruo, Takashi, Sugiura, Isamu, Takeuchi, Jin, Usui, Noriko, Naoe, Tomoki, Nakamura, Yusuke, Ohno, Ryuzo

Journal:

International Journal of Oncology

Year:

2007

Language:

english

File:

PDF, 211 KB

english, 2007

33

Liquid biopsy for the detection of clinical biomarkers in early breast cancer: new insights and challenges

Matsutani, Akiko, Udagawa, Chihiro, Matsunaga, Yuki, Nakamura, Seigo, Zembutsu, Hitoshi

Journal:

Pharmacogenomics

Year:

2020

File:

PDF, 934 KB

2020

34

Serial circulating tumour DNA analysis for locally advanced rectal cancer treated with preoperative therapy: prediction of pathological response and postoperative recurrence

Murahashi, Satoshi, Akiyoshi, Takashi, Sano, Takeshi, Fukunaga, Yosuke, Noda, Tetsuo, Ueno, Masashi, Zembutsu, Hitoshi

Journal:

British Journal of Cancer

Year:

2020

File:

PDF, 887 KB

2020

35

Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma

Nikolova, Dragomira, Zembutsu, Hitoshi, Sechanov, Tanio, Vidinov, Kalin, Kee, Low, Ivanova, Radina, Becheva, Elitza, Kocova, Miriana, Toncheva, Draga, Nakamura, Yusuke

Journal:

Oncology Reports

Year:

2008

Language:

english

File:

PDF, 344 KB

english, 2008

36

Evaluation of circulating tumor DNA as a biomarker in pancreatic cancer with liver metastasis

Uesato, Yasunori, Sasahira, Naoki, Ozaka, Masato, Sasaki, Takashi, Takatsuki, Mitsuhisa, Zembutsu, Hitoshi, Lee, Jung Weon

Journal:

Year:

2020

File:

PDF, 857 KB

2020

37

Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839

Zembutsu, Hitoshi, Ohnishi, Yasuyuki, Daigo, Yataro, Katagiri, Toyomasa, Kikuchi, Takefumi, Kakiuchi, Soji, Nishime, Chiyoko, Hirata, Koichi, Nakamura, Yusuke

Journal:

International Journal of Oncology

Year:

2003

Language:

english

File:

PDF, 2.85 MB

english, 2003

38

Significant Effect of Polymorphisms in CYP2D6 on Response to Tamoxifen Therapy for Breast Cancer: A Prospective Multicenter Study

Zembutsu, Hitoshi, Nakamura, Seigo, Akashi-Tanaka, Sadako, Kuwayama, Takashi, Watanabe, Chie, Takamaru, Tomoko, Takei, Hiroyuki, Ishikawa, Takashi, Miyahara, Kana, Matsumoto, Hiroshi, Hasegawa, Yoshie

Journal:

Clinical Cancer Research

Year:

2017

Language:

english

File:

PDF, 742 KB

english, 2017

39

Genetically Manipulated Human Embryonic Stem Cell-Derived Dendritic Cells with Immune Regulatory Function

Satoru Senju, Hirofumi Suemori, Hitoshi Zembutsu, Yasushi Uemura, Shinya Hirata, Daiki Fukuma, Hidetake Matsuyoshi, Manami Shimomura, Miwa Haruta, Satoshi Fukushima, Yusuke Matsunaga, Toyomasa Katagir

Journal:

Year:

2007

Language:

english

File:

PDF, 1.56 MB

english, 2007

40

Induction of tenascin-C by tumor-specific EWS-ETS fusion genes

Goichi Watanabe, Hiroyuki Nishimori, Hideto Irifune, Yasushi Sasaki, Setsuko Ishida, Hitoshi Zembutsu, Toshihiro Tanaka, Satoshi Kawaguchi, Takuro Wada, Jun-ichi Hata, Moriaki Kusakabe, Koichi Yoshida

Journal:

Genes, Chromosomes and Cancer

Year:

2003

Language:

english

File:

PDF, 386 KB

english, 2003

41

Dose-adjustment study of tamoxifen based onCYP2D6genotypes in Japanese breast cancer patients

Kazuma Kiyotani, Taisei Mushiroda, Chiyo K. Imamura, Yusuke Tanigawara, Naoya Hosono, Michiaki Kubo, Mitsunori Sasa, Yusuke Nakamura, Hitoshi Zembutsu

Journal:

Breast Cancer Research and Treatment

Year:

2012

Language:

english

File:

PDF, 460 KB

english, 2012

42

Pharmacogenomics toward personalized tamoxifen therapy for breast cancer

Zembutsu, Hitoshi

Journal:

Pharmacogenomics

Year:

2015

Language:

english

File:

PDF, 1.11 MB

english, 2015

43

A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population

Cha, Pei-Chieng, Zembutsu, Hitoshi, Takahashi, Atsushi, Kubo, Michiaki, Kamatani, Naoyuki, Nakamura, Yusuke

Journal:

Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 213 KB

english, 2012

44

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy

Goetz, Matthew P., Sangkuhl, Katrin, Guchelaar, Henk-Jan, Schwab, Matthias, Province, Michael, Whirl-Carrillo, Michelle, Symmans, W. Fraser, McLeod, Howard L., Ratain, Mark J., Zembutsu, Hitoshi, Gaed

Journal:

Clinical Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 311 KB

english, 2018

45

A prospective study to examine the accuracies and efficacies of prediction systems for response to neoadjuvant chemotherapy for muscle invasive bladder cancer

Kato, Yoichiro, Zembutsu, Hitoshi, Takata, Ryo, Matsuura, Tomohiko, Kato, Renpei, Kanehira, Mitsugu, Iwasaki, Kazuhiro, Yamada, Noriyuki, Katagiri, Toyomasa, Sugai, Tamotsu, Fujioka, Tomoaki, Nakamura

Journal:

Oncology Letters

Year:

2018

Language:

english

File:

PDF, 1004 KB

english, 2018

46

Intraductal papillary mucinous neoplasms of the pancreas: an analysis of protein expression and clinical features

Noriko Nishikawa, Yasutoshi Kimura, Kenji Okita, Hitoshi Zembutsu, Tomohisa Furuhata, Tadashi Katsuramaki, Sachiko Kimura, Hiroko Asanuma, Koichi Hirata

Journal:

Journal of Hepato-Biliary-Pancreatic Sciences

Year:

2006

Language:

english

File:

PDF, 497 KB

english, 2006

47

Clinical utility of circulating tumor DNA for colorectal cancer

Osumi, Hiroki, Shinozaki, Eiji, Yamaguchi, Kensei, Zembutsu, Hitoshi

Journal:

Year:

2019

Language:

english

File:

PDF, 449 KB

english, 2019

48

Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia

Kazuma Kiyotani, Taisei Mushiroda, Michiaki Kubo, Hitoshi Zembutsu, Yuichi Sugiyama, Yusuke Nakamura

Journal:

Year:

2008

Language:

english

File:

PDF, 101 KB

english, 2008

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